Non-Hodgkin lymphoma is a type of lymphoma (or cancer of the lymphatic system). There are over 60 types of non-Hodgkin lymphoma, and this disease group differs from Hodgkin lymphoma. Non-Hodgkin lymphoma can start anywhere in the body but most often begins in the lymph node, particularly in the neck. This type of blood cancer can also start in the liver or the spleen.
While non-Hodgkin lymphoma occurs in children and adults, its presentation varies in both segments. It is also the sixth most common cancer in the UK, with most people over the age of 75 being diagnosed with it.
The treatment for your non-Hodgkin lymphoma depends upon several factors, including the type and stage of your lymphoma, its grade, your symptoms, general health and treatment preferences.
Surgery is usually not a preferred treatment option for non-Hodgkin lymphoma. However, you may require surgery to:
If you have non-Hodgkin lymphoma, your doctor may recommend surgery for you if:
The cost of non-Hodgkin lymphoma surgery is affordable across the UK and depends upon the type and extent of the procedure. Procedures like splenectomy are usually performed via a laparoscopic or keyhole surgery that requires no hospital stay.
The primary treatment options for non-Hodgkin lymphoma include:
In low-grade non-Hodgkin lymphoma, chemotherapy drug may be injected into the veins or given as a tablet. Your doctor will determine the most suitable combination of drugs for you. While chemotherapy is given as an outpatient treatment in most cases, some medications may require you to stay the night at the hospital for monitoring.
A stem-cell transplant may follow intensive chemotherapy if your lymphoma has gone into remission and there is a risk of it recurring.
Advanced, high-grade non-Hodgkin lymphomas are treated with a combination of chemotherapy drugs that are given in cycles. Non-Hodgkin lymphomas that may spread to the brain or spinal cord may require chemotherapy with methotrexate.
Targeted drug therapy is given in some standard types of non-Hodgkin lymphomas or as part of a clinical trial. In some cases, targeted drug therapy may be given with chemotherapy for some types of non-Hodgkin lymphoma. Monoclonal antibodies are the most commonly used targeted drugs used for non-Hodgkin lymphoma.
Radiotherapy is usually recommended for early-stage (stage 1 or 2) non-Hodgkin lymphoma. You may have this treatment under the following conditions:
It may be challenging to cope with non-Hodgkin lymphoma and the various treatments. We get you. Our dedicated cancer care team supports you throughout your cancer journey, from booking appointments with the best private oncologists in the UK to helping you secure priority consultations for a second opinion on your diagnosis or treatment plan. Talk to us today!